Plexaderm® Skincare began simply with a desire to create products that truly work. From concept to commercial, everything we develop starts with one goal….to deliver REAL RESULTS supported by the latest in scientific and clinical research. Our products are designed to improve the most difficult signs of aging, from instantly reducing the look of wrinkles around the eyes to smoothing the appearance of crepey skin on the delicate neck and chest area. Every Plexaderm Skincare product uses science-backed and time-tested ingredients that provide results you can count on.Product safety is as important to us as product efficacy. Every Plexaderm product goes through a series of industry standard tests and processes to ensure safety, stability, and quality.
Plexaderm® (plexaderm.com) has 711 customer reviews on Five Star Index, with an average rating of 2.9 out of 5.
Also known as
plexaderm.com
Website
plexaderm.com
Category
Salons & Clinics
Location
Boca Raton, Florida
Listed on Five Star Index
2026
About these reviews
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The company replied to 89% of reviews.
Latest
Most recent review: October 2026.
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I have tried all kinds of eye cream to no avail. Plexaderm is a straight up awesome! Within 10 minutes my discolored bags under my eyes disappeared! Like magic! Thank you for all high quality product.
Response from Plexaderm®May 27, 2026
Thank you so much for your amazing feedback! We’re thrilled to hear that Plexaderm worked so well for you and that you saw results so quickly. Knowing that it helped reduce the appearance of your under-eye bags and gave you that “magic” moment truly means a lot to us.
We appreciate your support and kind words about the quality of our product. Thank you for being part of the Plexaderm family!
PM
Pam M.
Very temporary results (under 30 minutes)
This stuff pulls skin tight while it is drying, making wrinkles disappear. However, within 30 minutes the stuff cracks making skin appear wrinkled, dry and flaky. So, within 30 minutes you will look worse than when you started.
Response from Plexaderm®May 27, 2026
Thank you for sharing your experience. We’re sorry to hear the Plexaderm did not perform as expected for you. This formula is designed to provide a temporary tightening effect, but results can vary depending on skin type, application amount, and skincare products used.
We appreciate your honest feedback regarding the drying and flaking you experienced, and we will share your comments with our product team for review.
The Plexaderm formula is quite powerful and if too much is applied you may experience dryness, over tightening, or even see residue. We recommend trying a smaller sized application and spreading it out evenly. Please allow a full 10 minutes for Plexaderm to dry. If you are still experiencing residue, try dampening a cotton ball/swab and gently pat on the areas of concern, this will help take away any unwanted product.
If you’d like, please reach out to our customer experience team at 1-800-681-0366 so we can help with application tips or assist you further.
TG
Theresa G.
Two thumbs down
The product may be effective in reducing under eye bags and puffiness however it leaves residue now matter how little you use. It’s impossible to use the product and wear makeup.
Response from Plexaderm®May 19, 2026
Thank you for your feedback. We’re glad to hear you noticed improvement with under eye bags and puffiness, but we’re sorry to hear the residue made it difficult to wear with makeup.
For best results, we recommend applying a very small amount — about half a pea size for both under eyes — spreading it thin and evenly. Allow the Plexaderm to dry completely (up to 10 minutes) before applying any additional skincare or makeup.
When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. All makeup brands are different so you may need to adjust the Plexaderm-to-foundation ratio until you get the desired results.
We truly appreciate your honest review and will share your feedback with our product team.
KF
Kin F.
It does have a slight tightening effect… not so much a tightening effect more like putting a layer of something it’s very stiff, when you smile your cheeks go up and it makes very strange creases
It does have a slight tightening effect on the bags on your eyes, however when you smile or move your face you get lines below the bags because the product makes your skin have a little bit of a crusty layer, it does not last that long also and if you try to touch it up by putting more on you get a white crusty deposit. I did not find it useful socializing, it might add a little youth if you were doing yourself up for a photograph. But to go to a party where you’re talking and laughing the area doesn’t react like the rest of your face it’s like putting a little layer of concrete on your skin. It did not work out for me at all, even though they advertise it to death. Fortunately it’s inexpensive everyone can try and make up their own mind.
Response from Plexaderm®May 11, 2026
Thank you for taking the time to share such a thoughtful and detailed review. We're glad the Plexaderm was providing you with some tightening effect, however, sorry to hear the Plexaderm did not work as expected for you, especially during normal facial movement and social situations.
The white or “crusty” residue you described can sometimes happen if too much product is applied or if additional layers are added before the first application has fully set. For best results, we generally recommend applying a very small, thin even layer to clean, dry skin, gently dabbing it into place, and allowing it to dry completely while keeping facial movement minimal for a few minutes. Using less product often helps reduce stiffness and visible residue.
That said, we completely understand that everyone’s skin and expectations are different, and we truly appreciate your honest feedback about both the benefits and limitations you experienced. Your comments are valuable and will be shared with our team. Thank you again for giving it a try.
DB
damon B.
I purchased the 18 applications serum…
I purchased the 18 applications serum and used one full one on wrinkles every other day. It was too harsh for my skin gave me irritation and bumps. Called customer service to see if they could recommend anything to soothe the irritation , not much help but you would think after spending $50 on their product they would offer to send you something to ease the irritation. I don’t recommend this product if you have sensitive skin!
Response from Plexaderm®May 14, 2026
Thank you for sharing your experience. We’re sorry to hear the Plexaderm caused sensitivity. We always recommend discontinuing use immediately if any sensitivity or irritation occurs.
We also apologize that you did not feel fully supported by our customer experience team. Your feedback is important to us, and we appreciate you bringing this to our attention as we continue working to improve both our products and customer experience.
JF
Jason F.
Overall the product works really well
Overall the product works really well. Sometimes it works better on certain days for whatever reason. One thing I’d try and fix is that it leaves white lines under the eye lid which makes it look like someone is peeling from a sunburn. But I am overall very happy with the product.
Response from Plexaderm®May 8, 2026
Thank you for your thoughtful feedback! We’re so glad to hear you’re overall happy with the Plexaderm and seeing good results. We also appreciate you pointing out the white residue under the eyelid area. A few tips that may help, applying a very thin, even layer, making sure the skin is completely dry before application, and avoiding over-applying product can help reduce any visible residue or “peeling” effect. Dabbing away excess product before it fully sets may also help. We truly appreciate your feedback and will share it with our team as we continue improving the experience.
TO
Tommy
Sell a product that works
Sell a product that works
Response from Plexaderm®May 8, 2026
We’re sorry the Plexaderm didn’t meet your expectations. We’d really appreciate the chance to learn more about your experience and see how we can help. Please give our customer experience team a call at your convenience, 1-800-681-0366, we’d be happy to speak with you directly.
JS
Jan Schonblom F.
Does NOT WORK OR STAY ON AROUND MY…MOUTH EVER
Does NOT WORK OR STAY ON AROUND MY MOUTH. EVER. SOON AS I EAT, LINES ALL BACK. NO MATTER HOW CAREFUL I EAT OR DAB MY MOUTH. UNDER EYES YES. AROUND MOUTH. NEVER
Response from Plexaderm®May 8, 2026
Thanks for sharing your experience. We’re glad to hear it works well for your under-eyes, but we understand how frustrating it is when it doesn’t hold up around the mouth area, especially after eating or drinking. That area naturally has much more movement, which can make products wear differently. We truly appreciate your honest feedback and will share it with our team.