Regenexx pioneered interventional orthopedics, using the body’s own cells and natural healing abilities to treat orthopedic conditions and injuries non-surgically. Our treatment protocols are grounded in ongoing research and continuously refined through our dedicated R&D team, specialized laboratory, and patient-reported outcomes tracking data.Regenexx has developed the most advanced processing and treatment techniques used today and has published a significant share of the worldwide research on the use of bone marrow concentrate for orthopedic conditions.Only a select group of highly-skilled musculoskeletal doctors are licensed to perform regenerative orthopedic procedures using Regenexx treatment protocols and injectates. The doctors in our licensed physician network are independent medical providers and are not employees or agents of Regenexx. They have chosen to license Regenexx technology and treatment protocols for use in their regenerative orthopedic practice.Regenexx is dedicated to advancing orthobiologic treatments, research, and technology to support patients seeking alternatives to surgery or pain medications.Regenexx maintains an active patient registry that tracks patients’ progress and side effects, post-procedure using Regenexx injectates. Our outcomes database contains records on tens of thousands of procedures performed by physicians in the licensed Regenexx network. Those outcomes are transparently published and updated monthly at https://regenexx.com/results/Like all medical procedures, regenerative procedures using Regenexx injectates have a success and failure rate. Patient reviews on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.
Regenexx (regenexx.com) has 997 customer reviews on Five Star Index, with an average rating of 4.5 out of 5.
Also known as
regenexx.com
Website
regenexx.com
Category
Medical Specialists
Location
Des Moines, Iowa
Listed on Five Star Index
2026
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Most recent review: October 2026.
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Extremely professional, caring and provided great guidance as what to expect from a procedure along with being honest about opinions that your situation is not treatable using their procedure...ETHICAL!
I've had several different treatments done and all met expectations...
CA
Catherine
Would have liked more information on…
Would have liked more information on use of strap on braces and how often and when to use them....Unclear messaging on this. Otherwise very good experience.
AJ
AJM
I have had stem cell injections in my…
I have had stem cell injections in my right hip and right knee and I can’t believe the difference. I am able to walk, hike, garden and excercise with no pain. I have and would recommend Regenexx to friends and family.
PA
Paula
No miracle, but I am definitely better
I feel like the communication with the doctor was excellent. Dr, Stiene with Beacon Orthopedics made sure I understood all aspects of treatment and recovery. As far as the treatment itself, it went very smoothly. Definitely better than surgery! Regarding outcomes, my knee is about 70% better at this point. Definitely less pain than before treatment, but still some pain and lack of mobility.
SR
Stephen R.
My knees hurt everyday as I tried to…
My knees hurt everyday as I tried to workout running, biking or lifting, after 15 years in the military and 20 years as JH/HS XC/Track coach. I thought the end of athletics was near as a 60 year old. My friends told me about Regenexx and they were encouraging and right. Dr. Hyzy did procedures on both knees and a PRP on my lower back. I can stand and coach 3 hours a days/5 days/ week and last at all day track meets. I am increasing my bike mileage and can stay in the group with local Saturday morning ride crews. I am back to riding over 100 miles and climbing more than 2,000m per week without pain and recovering. I was amazed my seat height has gone up 2 inches and it feels great! Never quit- keep going on and enjoy life!
BR
Bryan
Stem cells procedure to right hip has…
Stem cells procedure to right hip has improved stiffness (reduced)
Movement & pain management by about 90%
BA
Barbara
Amazing Results of Stem Cell Tx After Partial Meniscectomy.
My husband used Promedica Regeverative Medicine in Toledo, one of Regenexx’s clinics, for treatment of pain, arthritis, and laxity and instability of his right knee after having a military duty related injury to his right meniscus. A good orthopedic surgeon removed most of the medial meniscus, and because he was experiencing continued pain and instability, he suggested he either could have a partial knee replacement or find a place where perhaps he could have stem cell treatment done. Since Ken was not ready to have parts of his anatomy amputated and I appreciated his honesty in suggesting My husband research the stem cell option.
He received Regenexx prolotherapy, stem cell treatment, and PRP at the Toledo, Ohio clinic a year ago now. Ken’s pain level for about 25 years due to several meniscus tears had been no less than 7 and up to 10 at it’s worst. He’d just sucked it up. About 6 weeks after the
procedure, he got out of bed one morning and
realized he was in no pain whatsoever. He always awoke with pain at about a 3 or 4. That
was a watershed moment.
Since then, he still awakens with no pain unless he’s been overdoing it at work, in the military, or in
the martial arts. Ken’s getting used to that new normal. On his worst days he might hit a 3, maybe 4 out of 10, but that, again, is with heavy use of his knee, pivoting and so forth.
Ken has an appointment to receive a PRP booster next month, as his doctor, Dr. Rennels noted some laxity in his MCL, which makes sense, and because I read that Dr. Centeno and some of the other docs at Regenexx do this from time to time as well.
I would beg anyone who is considering any
orthopedic surgery, or anyone with arthritis, at least have an evaluation at a Regenexx clinic to see if you’re a good candidate. They will be frank with you. In the interest of full disclosure, it didn’t grow his missing meniscus back. Had he had the procedure rather than the earlier surgery, mandated by the military due to other quadriceps tears in the same knee, it might well have had that regenerated. However, the treatment stabilized his knee, strengthened his tendons and ligaments, vastly decreased his pain, allows him to accurately gauge how he’s using or overusing his knee, and has brought Ken back to something like normal after so many years of abusing his knee. It really is nothing short of remarkable and I would recommend it to anyone because of the improvement my husband has had.
(He is dyslexia, so he asked me to submit this on his behalf, giving his answers)
JA
Jay
Dr. Hyzy
Dr. Hazy is excellent. Extremely knowledgeable and helpful. Regenexx is the real deal. Don’t waste your time or money anywhere else.