Plexaderm® Skincare began simply with a desire to create products that truly work. From concept to commercial, everything we develop starts with one goal….to deliver REAL RESULTS supported by the latest in scientific and clinical research. Our products are designed to improve the most difficult signs of aging, from instantly reducing the look of wrinkles around the eyes to smoothing the appearance of crepey skin on the delicate neck and chest area. Every Plexaderm Skincare product uses science-backed and time-tested ingredients that provide results you can count on.Product safety is as important to us as product efficacy. Every Plexaderm product goes through a series of industry standard tests and processes to ensure safety, stability, and quality.
Plexaderm® (plexaderm.com) has 711 customer reviews on Five Star Index, with an average rating of 2.9 out of 5.
Also known as
plexaderm.com
Website
plexaderm.com
Category
Salons & Clinics
Location
Boca Raton, Florida
Listed on Five Star Index
2026
About these reviews
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The company replied to 89% of reviews.
Latest
Most recent review: October 2026.
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Thanks for your review. We are very sorry to hear about your purchasing experience with us. Usually, gift cards can be used however, it's important to call the gift card company and update your billing and shipping address to the card you're looking to purchase with. Our systems can be sensitive and may not allow a purchase without this information on file. Should you have any questions, please give us a call at 1-800-681-0366. We're happy to help!
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Terri F.
I used the trial pack of Plexiderm and…
I used the trial pack ofPlexiderm and I'm glad I did! It does do what it claims on t.v. But the downsides far outweigh the benefits. It does tighten the skin very well, but don't rub it because it pills badly. Flakes everywhere. It's also skin drying. It might be ok for $15 tops. If you're dying to try it get the trial pack.
Response from Plexaderm®May 12, 2025
Thanks for taking the time to share your experience with the Plexaderm Rapid Reduction Serum. We're glad to hear Plexaderm does what it claims to do and tightens the skin well. You might be experiencing residue due to applying too much product in the areas of concern. The Plexaderm formula is quite powerful if too much is applied you may experience dryness, over-tightening, or even see residue. I recommend trying a smaller-sized application and spreading it out evenly. Please allow a full 10 minutes for Plexaderm to dry. If you are still experiencing residue, try dampening a cotton ball/swab and gently pat on the areas of concern, this will help take away any unwanted product. Should you have any additional concerns, please give us a call at 1-800-681-0366. We will be more than happy to help walk you through application tips.
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Del M.
I have been using your product for… not as good as it used to be
I have been using your product for approximately 2530 years but I do notice the last three that I purchased. I don’t know if they’re old or what the problem is because I haven’t changed my routine at all, but I do notice that when I put it on the same way, I’ve always put it on. It’s Kiki and I have to get a Q-tip moisten it and get the cake scaly product off of my eyes so they don’t look bad so I’m actually wondering if there’s something wrong with the last order
Response from Plexaderm®May 1, 2025
Thanks so much for taking the time to provide this feedback. First, we want to thank you for being a loyal customer for 2530 years! We are very sorry to hear you're not seeing the Plexaderm be as effective as it has been previously. The only thing that's changed over the years is the packaging and applicator. The formula remains the same. However. we would love to know more about what you're experiencing and collect more information. In addition, we'd love to make things right. If it's not too much trouble, please give us a call at 1-800-681-0366. We look forward to hearing from you!
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Elliot R.
For me
For me, this product did absolutely nothing. On my forhead wrinkles, before and after...nothing. On wrinkles around my mouth, before and after....nothing. On eye bags, before and after....nothing. In fact, the tightning of skin under my eyes created more wrinkles, that I did not have before using this product. Now understand, these were my results. I can't say how they would work on others. But for me, this product did absolutely nothing.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. We are very sorry to hear about your disappointment
with the Plexadxerm Rapid Reduction Serum. Your satisfaction is important to us and wanted to provide you with some product usage tips when it comes to applying Plexaderm.
You'll want to apply Plexaderm to a freshly cleansed face. Once applied, it is important to remain still during the Plexaderm application process. Refrain from facial movements for approximately 10 minutes while Plexaderm forms an invisible bond with your skin. When applying Plexaderm you need to spread the serum out evenly to avoid over-tighting, which as you mentioned can create more wrinkles.
When using a moisturizer we recommend one that is oil-free, as oils break down the tightening effect that Plexaderm creates. Please note that results can vary from product to product. If you're interested, we developed a moisturizer that pairs perfectly with our serum, the Plex-Perfect Daily Moisturizer.
If you're using Plexaderm with makeup, it's best to apply makeup after Plexaderm has set, being as light as possible over the Plexaderm areas and avoiding rubbing. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. Eyeshadows, liner, mascara, and blush are all good products to use with Plexaderm.
We hope this information was helpful. Should you have any questions or need further assistance, give us a call at 1-800-681-0366. Every purchase is backed with a 30 day money back guarantee, we will be happy to look into your eligibility for you should you decide Plexaderm is not for you.
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Deb T.
Under eye problems when using plexiderm
When I apply Plexiderm to the bags under my eyes, it sometimes leaves a small pouch or crinkles under my eyes. I then have to wash it off & reapply. Sometimes I have to do it 3 times.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. The application process is key, be sure to evenly spread out the serum and allow it to set for 10 minutes. A little goes a long way, you may be applying too much product. Should you need further assistance, please call us at 1-800-681-0366. We're happy to help!
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Francine
Happy with it!
I'm pleased with the way Plexaderm works on my under eye bags.
Response from Plexaderm®Apr 28, 2025
We're happy to hear you're pleased with the way Plexaderm works on your under-eye bags. Thanks for taking the time to leave a review.
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Christina T.
Plexaderm works if you don't wear…
Plexaderm works if you don't wear makeup. It literally doesn't go under or over makeup and stays on. As soon as you try to use concealor before or after it balls up and come off. Not worth the money. It drys out under you eyes also. My bf used it to and doesn't wear makeup and it only lasted maybe a hour . Not worth the money.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. All makeup brands are different so you may need to adjust the Plexaderm-to-foundation ratio until you get the desired results. We hope this helps, should you need further assistance, please call us at 1-800-681-0366. We're here to help!
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Evelyn
Plexaderm has helped me feel better…
Plexaderm has helped me feel better when I look in the mirror in some mornings. For example, When I sleep late and wake up wake up looking tired with minor bags. although I do not fully depend on it, I feel comfortable.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. We're happy to hear Plexaderm helps make you feel better and has become a vital part of your routine. Thanks for being part of the Plexaderm community!
