Plexaderm® Skincare began simply with a desire to create products that truly work. From concept to commercial, everything we develop starts with one goal….to deliver REAL RESULTS supported by the latest in scientific and clinical research. Our products are designed to improve the most difficult signs of aging, from instantly reducing the look of wrinkles around the eyes to smoothing the appearance of crepey skin on the delicate neck and chest area. Every Plexaderm Skincare product uses science-backed and time-tested ingredients that provide results you can count on.Product safety is as important to us as product efficacy. Every Plexaderm product goes through a series of industry standard tests and processes to ensure safety, stability, and quality.
Plexaderm® (plexaderm.com) has 711 customer reviews on Five Star Index, with an average rating of 2.9 out of 5.
Also known as
plexaderm.com
Website
plexaderm.com
Category
Salons & Clinics
Location
Boca Raton, Florida
Listed on Five Star Index
2026
About these reviews
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The company replied to 89% of reviews.
Latest
Most recent review: October 2026.
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I might as well have used Elmers glue.not even worth 1 star.
Response from Plexaderm®Mar 30, 2026
We’re sorry to hear this didn’t meet your expectations. We understand how frustrating it is to invest in a product and not see the results you were hoping for.
Our Plexaderm Rapid Reduction Serum is designed to deliver temporary tightening effects, but results can vary depending on individual skin type and application. We appreciate you giving it a try and sharing your honest feedback.
If you’d like, please reach out to our customer experience team with your order details, we’d be happy to assist you further and explore available options.
DD
Danielle D.
Disappointing Results & Lasting Puffiness
I treated myself to the 10ml Rapid Reduction Serum ($54.13) for Christmas after seeing so many good reviews, but it really let me down. I followed the directions to a T on my forehead and smile lines back in January, but saw basically no difference. I decided to give it one last shot on my right under-eye to compare it to my left. Not only did it fail to work, but I woke up the next morning with a bloodshot eyeball and puffy eye bag that wasn't there before. When I tried the serum on the very bag it caused, it still did nothing! It’s been three months and my eyeball is still bloodshot and the swelling has decreased some but it still hasn't fully gone away, while my untreated eye looks totally normal. I’m honestly so bummed that this pricey product didn't just fail—it actually made my eye look worse.
I take back what I previously said about their customer service. Not only did they give me a full refund but they actually called. You can definitely buy this product and know that their customer service is going to make it right if something goes wrong.
Response from Plexaderm®Mar 30, 2026
Thank you for sharing your experience. We’re really sorry to hear this. That’s definitely not the result we want for anyone using our Rapid Reduction Serum, especially after you followed the directions so carefully.
While many customers see temporary tightening effects, we understand that results can vary, and what you’re describing, sounds like you experienced sensitivity.
We strongly recommend discontinuing use and if you haven’t already and consulting with a healthcare professional regarding the ongoing symptoms. Your safety and comfort come first.
We’d also really appreciate the opportunity to make this right. Please reach out to our customer experience team with your order details so we can look into a refund or further assist you.
Thank you again for your honest feedback, it helps us improve and better support our customers.
AH
Angela H.
Disappointed
I was excited about this product. I read all the instructions first. I used it as directed, and the product turned a dark color. I figured that
I applied too much. I rinsed it off and started from scratch with a smaller amount. Then, it turned white, and began to peel. I tried it a third time the exact same thing ocurred. I saw no difference. I spent $64. I'm so disappointed. I didn't think it would totally change my puffiness, but absolutely no difference and it made my skin look worse/dry. I feel like I was taken advantage of and have no recourse. Plexaderm responded below that it was too much product. That's not the case the second and third time. I used way less and it didn't matter.
Response from Plexaderm®Mar 19, 2026
Thank you for sharing your experience, we’re really sorry to hear how disappointing this has been.
From what you’ve described, it sounds like too much product may have been applied. When the formula leaves a visible residue, turns white, or begins to peel, it’s typically a sign that a smaller amount is needed. Using a very minimal layer and gently dabbing it in can help it absorb properly and avoid that effect.
We understand how frustrating it is not to see the results you were hoping for, especially after giving it multiple tries. Please know that we offer a 30-day money-back guarantee. If your order falls within our policy, we’d be happy to help you with a return. You can also give us a call at 1-800-681-0366, we’d be glad to walk you through application tips to help you get the best possible results.
We truly appreciate you giving the Plexaderm Rapid Reduction Serum a try and the opportunity to make this right.
GD
Gwen Davis-CLP, M.
This product sucks and feels awful on…
This product sucks and feels awful on your skin. It leave a horrible dry film and half the time amplifies your wrinkles if it works at all.
The first time I ordered was when product first came out and it worked great. It was a white cream that soaked in nicely and worked. When I told company this they argued with me like I was wrong. Claiming they had not changed their formula and that it has always been made with clay. BS. They claim you get a 90 day money back guarantee but when you request it they say oh no only 30 day money back guarantee and will not honor it. Lots of false advertising. Product barely works if you apply it just so and even if you do get results it feels so horrible on the skin you can't wait to get it off. Product used to be good. Now company lies. First batch of product I received didn't work at all. So then sent me more from a different batch. It worked slightly but was still not like the commercials. And like I said feels so awful you can't wait to remove it. Awful product, awful company, don't waste your money here because they do not honor money back guarantee.
Response from Plexaderm®Mar 19, 2026
Thank you for taking the time to share your experience, we’re really sorry to hear how disappointed you’ve been.
We do want to clarify a couple of points: The Plexaderm Rapid Reduction Serum has always been formulated as a pink-tinted serum, and the formula has not changed. We understand this may differ from your expectations, and we’re sorry for any confusion that may have caused.
Regarding our policy, we offer a 30-day money-back guarantee, and we apologize if there was any misunderstanding around that. That’s certainly not the experience we want anyone to have.
After reviewing your account, we can confirm that your request fell outside of our 30-day money-back guarantee window. However, as a courtesy, we did provide a replacement to try to make things right.
For best results and to help minimize the residue you mentioned, we recommend:
- Applying a thin, even layer to clean, dry skin
- Gently spreading the product out without over-applying
- Allowing it to fully dry for about 10 minutes
- Avoiding facial movements while it sets
If you’re still having concerns, we’d truly appreciate the chance to assist further. Please feel free to reach out to our Customer Experience team at 1-800-681-0366 so we can continue working toward a resolution.
Thank you for sharing your thoughts with us.
YJ
Yaz J.
I appreciate Plexaderm's response
I appreciate Plexaderm's response to my review. I use a water based foundation and not a heavy amount. I also avoided applying any moisturizer or any other product on my clean, dry skin (according to the directions). It's good to acknowledge that this product just does not work on ALL skin types. In reality, NO skin product is cookie-cutter so to admit that it doesn't work for everyone, no matter how much you'd like it to, is a noble gesture indeed.
PN
Pamela N.
DO NOT buy this product
DO NOT buy this product! The trial package was set in small "buttons" on a sheet. Very hard to get to product. Also, did not work at all on any wrinkles, whether fine lines or other. Dries the treated areas exponentially, and flakes, and moisturizer doesn't help. Waste of time and money.
Response from Plexaderm®Mar 16, 2026
Thank you for sharing your feedback. We’re sorry to hear that your experience with the trial pack did not meet your expectations.
The sample packs are designed to contain small, single-use portions, though we understand they can sometimes be difficult to open or access, and we appreciate you bringing that to our attention.
For best results, the Plexaderm Rapid Reduction should be applied in a very small amount (about a pea-sized amount or less) to clean, completely dry skin. It’s also important to allow the product to fully set before applying additional skincare or makeup. When using moisturizers, serums, or makeup, we recommend that they be water-based, as oil-based products can interfere with how the formula sets and may sometimes cause flaking or visible residue.
Plexaderm is designed to provide temporary smoothing benefits for many users, but results can vary depending on skin type, application technique, and the other products used in a skincare routine.
If you would like assistance or tips on application, our team would be happy to help. Please feel free to give us a call 1-800-681-0366 so we can better understand your experience and see how we may assist you further. We truly appreciate your feedback.
RL
Randy L.
I started to order the $14.95 sample…
I started to order the $14.95 sample but changed mind after I had completed my information clicked the cancel button, noticed the following morning it's pending on my bank account, so I called their customer service number and was told it shipped already ( supposedly in 10 hours-overnigh) said they can't cancel because it shipped already
So made sure nothing else is ever shipped and charged ever again.
The advertisement and the website is a typical bait and switch.
I don't care how well it works I wontever order anything from them ever again
Response from Plexaderm®Mar 5, 2026
Thank you for sharing your feedback. We're sorry to hear about your experience and understand how frustrating that situation must have felt.
Once an order is processed, orders are typically processed and shipped quickly, which can sometimes make cancellations difficult if the shipment has already been prepared. That said, we always want our customers to feel confident about their purchase.
Please remember that we offer a 30-day money-back guarantee, and our team would be happy to review your order and help resolve the situation for you. We’d appreciate the opportunity to make this right.
Please give our customer experience team a call so we can look into your order and assist you further at 1-800-681-0366.
GH
Gaylyn H.
It Works Wonders—But The Cost!
I have used Plexaderm for several years. I am 61 and have always rubbed my eyes, even as a teenager, so I have horrible bags under my eyes. Plexaderm works wonderfully for me. I mix a tiny amount of my foundation with it in my palm then apply to each eye separately. I do this for two reasons: Plexaderm begins to dry quickly so if I try to do both eyes at the same time the second eye will be flaky; and I’ve learned the right amount for each eye is different so they must be done individually.
I also used Plexaderm on the wrinkles forming around one side of my mouth. It works wonderfully there also and does not crack during the day.
For me, there are two keys to getting all day wear without flaking: trial and error to determine the amount needed for each eye and mouth area because they are different for me; and taking the 7-10 minutes that Plexaderm needs to set before doing anything else. Yes, my husband says I look strange standing there staring into the mirror without moving my eyes or mouth, but whatever.
My only problem with Plexaderm is the cost. I cannot afford to use it when I know I will be home all day or when I am going out to visit with family or close friends. The cost is just too prohibitive.
Response from Plexaderm®Feb 26, 2026
Thank you so much for taking the time to share your detailed experience with Plexaderm. We truly appreciate hearing how well it’s working for you!
It’s wonderful to know that you’ve found an application method that gives you consistent, all-day results. Mixing a small amount with foundation and applying each area individually is a great tip, and you’re absolutely right, allowing the full 10 minutes for it to set can make all the difference in achieving a smooth, flake-free finish. Your patience (even if it earns a few funny looks!) clearly pays off.
We also understand your concern about the cost. We know how important it is to feel confident using a product regularly without worrying about the expense. We frequently offer promotions, subscription savings, and special discounts that can help make it more affordable. We encourage you to check our website or sign up for email updates so you can take advantage of those opportunities.
Thank you again for your thoughtful feedback and for being a loyal customer over the years. We’re so glad Plexaderm has been able to deliver the results you were looking for!
