Regenexx pioneered interventional orthopedics, using the body’s own cells and natural healing abilities to treat orthopedic conditions and injuries non-surgically. Our treatment protocols are grounded in ongoing research and continuously refined through our dedicated R&D team, specialized laboratory, and patient-reported outcomes tracking data.Regenexx has developed the most advanced processing and treatment techniques used today and has published a significant share of the worldwide research on the use of bone marrow concentrate for orthopedic conditions.Only a select group of highly-skilled musculoskeletal doctors are licensed to perform regenerative orthopedic procedures using Regenexx treatment protocols and injectates. The doctors in our licensed physician network are independent medical providers and are not employees or agents of Regenexx. They have chosen to license Regenexx technology and treatment protocols for use in their regenerative orthopedic practice.Regenexx is dedicated to advancing orthobiologic treatments, research, and technology to support patients seeking alternatives to surgery or pain medications.Regenexx maintains an active patient registry that tracks patients’ progress and side effects, post-procedure using Regenexx injectates. Our outcomes database contains records on tens of thousands of procedures performed by physicians in the licensed Regenexx network. Those outcomes are transparently published and updated monthly at https://regenexx.com/results/Like all medical procedures, regenerative procedures using Regenexx injectates have a success and failure rate. Patient reviews on this site should not be interpreted as a statement on the effectiveness of our treatments for anyone else.
Regenexx (regenexx.com) has 997 customer reviews on Five Star Index, with an average rating of 4.5 out of 5.
Also known as
regenexx.com
Website
regenexx.com
Category
Medical Specialists
Location
Des Moines, Iowa
Listed on Five Star Index
2026
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Most recent review: October 2026.
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Dr. Cohen did a through exam & explaination of my knees during the consultation, giving me confidence to proceed. The procedure went very well. Everyone was friendly, helpful, & supportive. The results have been great. So glad I did this rather than knee replacements.
SK
Steve K.
PRP Review
This review is for PRP, not stem cell because it was good enough for me. I heard about Regenexx in 2014 from a neighbor. I was having issues with my spine from the top of my neck down to and including SI Joints/hips. I had trouble turning my head past 45 degrees without it locking up, my middle back was killing me and my knees hurt just stepping off a curb much less walking down stairs. My legs/hips would be stiff after getting out of the car after a long drive. Cervical MRI showed 2 moderately and 2 mildly bulged discs in my cervical alone. So we started there with PRP but Dr. Handleman also went lower to the bottom of my shoulder blades. After 3 procedures, I did a thoracic MRI and the problems it showed were below the upper the thoracic we did. Worst was a severely bulged disc in the middle back at T9-T10. So we did 4 procedures on that along with some lumbar and SI Joints. After the 4 procedures I re did the Thoracic MRI and the bone spurs are still there but no more bulged disc. Looks like all the other discs. I'm sure it healed the ligaments too because after 2.5 years the bone spurs were no worse, so the instability must be pretty much gone. Less than two weeks ago we did a 4th procedure on the upper neck/2nd on SI Joints and I'm feeling great. I can assure you if I re did my cervical MRI in a month it wouldn't find a bulged disc. Also did 1 procedure a while back for miniscus/cartilage and quad tendons both knees and they feel much better. As far as instant results; before my knee procedure I got acute tendonitis in my right shin tendon. You could feel and hear the creeking as I raised my right toe up and down. I could barely walk. When I came in to do my knees Dr Handleman also put some PRP into that tendon. Next day creeking gone, I'm walking no problem, and it never came back. I'm sure that problem was a result of pinched nerves in my back/SI Joints.
For some perspective....I'm 44 years old and consider myself to be in excellent shape. I've never had orthopedic surgery. I've never smoked. I don't take pharmaceuticals, prescription or over the counter. I weight train and do situps at the gym as well as jog. Even when I was having my issues, I pushed through it. I try to eat healthy, fruit and raw vegetables every day, raw nuts, low carbs, a lot of water. I've been taking high quality supplements since I was in my early 20's and have been adding as time went on from Puritan's Pride and Life Extension. Why I mention this is because all this plays a huge role in your results/outcome. I've had incredible results but that doesn't mean everyone should expect the same. That being said, you owe it to yourself to try this before surgery, you got nothing to lose. These procedures absolutely work and have been worth every penny and more. This is true health care and the future of orthopedics. It's just a shame that insurance companies are so stubborn about covering it. Eventually they will, but I didn't have that kind of time. The earlier you catch a problem the easier it is to fix it.....wait for a severely bulged disc to rupture and you'll be lucky if you heal it with stem cell.
RH
Robert H.
Excellent staff
Excellent staff, facility and procedures. 2 plus years after stem cells in both knees and in very pleased with the results. Only hiccup was when trying to utilize a health savings account. Three try's to get it submitted. Dr Jacksons is the best
AK
Alan Karp M.
Happy Camper
I was rated a fair to poor candidate initially. My physician was very upfront about this. That being said I proceeded with the stem cell treatment and I am ever so glad that I did. My only alternative was a total knee replacement. This based on my evaluation by a sports medicine specialist and team physician for the Dallas Cowboys. He stated that I should get a total knee replacement when I was "ready." At that time I could not ski more than an hour before the pain sent me to the bar! I am now able to ski for a few hours and walk 18 holes of golf. Up and down stairs is not a problem at all. I am 20 months out from the procedure and if anything over time I have improved to the point I am 80% better than I was. I do use turmeric daily and Arnica gel from time to time. Knee replacement is the furthest thing from my mind.
I went to the Broomfield office and my physician there was Dr. John Pitts. As far as I am concerned he is an absolute rock star! Very personable and technically he has outstanding skills. Minimal discomfort with the procedure. I requested him based on recommendation from a university professor who develops titanium knee implants! If I had it to do over again there is nothing I would change!
TY
Tsz yin timothy Y.
I have done Regennex C over several …
I have done Regennex C over several years for both my knees. I have had several major knee issues including medial meniscal tears and partial ACL tears. I believe Regennex C provided significant improvement to both my knees, such that I am now able to return to the sport I love and play at an enjoyable level.
FS
F. S.
2 years post-procedure
It has been 2 yrs since my stem cell treatment to both my knees. The pain and limited motion is essentially gone. I would do this again in a heartbeat! The staff, doctors very professional and knowledgeable. Kudos to my Regenexx team!
YS
YASKOW, S.
I wish I had never had the 2 meniscus …
I wish I had never had the 2 meniscus surgeries I had at age 20 and again at 47. By age 56 I could no longer play tennis and could barely coach my 2 tennis teams. I got cortisone shots, hyrolonic injections, took NSAIDS almost every day, couldn't sleep at night, routinely ice and rested my knee just to be able to do basic home activities, go up or down stairs, walk on uneven ground and felt generally unstable on my knee. I could no longer run road races or just run for general fitness. I had to go back to the pool for a solid workout and even swimming was difficult.
After my stem cell procedure my quality of life slowly returned. No more NSAIDS, I follow the nutritional guidelines and take the supplements suggested. I excercise, walk and swim @5 miles a week in the pool and best of all am not in constant pain and no longer worried about my leg strength and stability. At 59 years old I still have bone spurs and can not expect to run 5 and 10Ks after what the 2 surgeries did to my joint but after Regenexx I live pain free. I am interested in preserving as much of what I have as long as I can so I am extremely happy with the results of my procedure. I am able to keep up with the kids I coach on my tennis teams and a very active physical lifestyle. I am angry insurance does not cover the procedure especially when it has such positive results.