At ZignaGenix, we believe healthcare should be personal, compassionate, and focused on helping people live healthier, more fulfilling lives.Our mission is to improve the quality of life of every patient we serve by providing access to advanced regenerative medicine, innovative wellness therapies, and personalized treatment programs designed to support the body's natural ability to heal and recover.With medical clinics in Tijuana, Puerto Vallarta, and Cancún, Mexico, our experienced physicians and healthcare professionals are dedicated to delivering exceptional patient care, education, safety, and support throughout every step of the treatment journey.We understand that many of our patients come to us after years of searching for answers. That's why we take the time to listen, educate, and develop individualized treatment strategies focused on each patient's unique goals and needs.At ZignaGenix, people come first. Our commitment extends beyond treatments—we strive to create an experience built on trust, integrity, innovation, and genuine care. Every day, we work to help our patients regain hope, restore function, optimize wellness, and achieve a better quality of life.Because when our patients succeed, we succeed.
Zignagenix (zignagenix.com) has 86 customer reviews on Five Star Index, with an average rating of 5.0 out of 5.
Also known as
zignagenix.com
Website
zignagenix.com
Category
Clinics
Listed on Five Star Index
2026
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Most recent review: October 2026.
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Manuel is why I chose Zingagenix. So kind and helpful.
Manuel helped me maneuver through my process so perfectly. The dr and other staff are awesome too. They don’t let you get uncomfortable, they offer treats and cozy blankets. I’m already planning on going back and I went September 30.
Response from ZignagenixDec 3, 2025
Thank you so much for your amazing 5-star review! We’re thrilled to hear that Manuel made such a positive impact on your experience — he truly is one of the best, and we’re grateful to have him on our team.
Our entire staff works hard to create a comfortable, supportive environment, and it means a lot to hear that you felt cared for from start to finish. We love that you noticed the small touches — the blankets, the treats, and the personalized attention.
We’re honored you chose ZignaGenix for your care, and we’re excited to welcome you back whenever you’re ready. Thank you for trusting us! 🙏💙
SP
Shola P.
12/10 quality of care and results!
My name is Shola. I am from Northern BC in Canada. Having suffered with extreme debilitating knee pain since I was 31, it was very challenging to manage. At age 34 I was diagnosed with early onset osteoarthritis and told I would not be able to receive any surgical treatment for at least 20 years. 😳😫 Everything changed when I found stem cells.
I have had stem cell therapy twice from two different companies using two different methods. Both experiences had their own benefits. However, the experience with Zignagenix stem cell clinic was incredible.
I received my stem cells from Zignagenix on October 29th of 2021. (Trust Pilot won’t allow me to write a review past 1 year).
The level of care offered by Zignagenix is second to none. The quality of stem cells, the process that they use to harvest and cherry pick the most robust cells and then culture only those ones is state of the art. The criteria that people must meet to be allowed to donate their umbilical cord blood for the stem cell harvesting is at a standard so high that I feel safe and secure knowing that I am getting only the highest quality of stem cells from Zignagenix. These are just some of the reasons why I trust Zignagenix literally with my life and because of this I will continue to enjoy the deep healing benefits of their stem cell therapy for many years.
I experienced 75% relief from pain and inflammation within 4 days of my last stem cell treatment vs the same relief in one month from the previous company that I had received it from. I was immediately able to stop taking all anti inflammatories and over the course of the next year I just felt better and better and carried that into the next 3 years with virtually no pain. Without Zignagenix Stem Cell Therapy I would be living in a wheelchair with a vastly reduced quality of life and still medicating for extreme pain.
Zignagenix has truly given me my life back and enables me to live as actively and vibrantly as I am truly meant to.
I can’t even express how grateful I am. Thank you Zignagenix. You have my highest recommendation and deepest gratitude. ❤️🙏🏽💃🏻
Response from ZignagenixOct 27, 2025
Dear Shola,
Thank you from the bottom of our hearts for sharing your incredible story. Hearing how your life has been transformed through stem cell therapy truly inspires our entire team. Your journey—from years of pain and limitation to living freely and vibrantly again—is exactly why we do what we do.
We’re honored that you placed your trust in ZignaGenix and our process. Our mission has always been to deliver world-class regenerative medicine through uncompromising quality, care, and science—and your words affirm that we’re fulfilling that mission.
Your courage, positivity, and dedication to healing are remarkable, and it means so much to know that you continue to thrive years after your treatment. Thank you again for allowing us to be part of your journey and for recommending ZignaGenix with such heartfelt sincerity.
With deep gratitude and best wishes for your continued health and vitality,
The ZignaGenix Team
🌿 Cellular Regeneration. Transforming Health. Redefining Possibilities.
RZ
Randall Z.
My Experience with ZignaGenix Tijuana
Diagnosed with Stage IV prostate cancer with bone metastases in April 2024. I was not interested in traditional treatments such as hormone
replacement therapy (HRT) or chemotherapy.
Instead, I turned to alternative therapies, beginning with Rick Simpson Oil and naturopathic supplements. Over the next year and a half, I added Ivermectin, Fenbendazole, Vitamin B17, Artemisinin, turmeric, and several others.
My bloodwork has shown concerning trends: continually rising PSA levels, a declining red blood cell count, and a low Absolute Lymphocyte Count (ALC). I came across research by Dr. Soon-Shiong highlighting that a prolonged ALC below 1000 can shorten lifespan. Reviewing my own results, mine had been under 1000 for several months.
I reached out to a supportive relative and shared my data. He suggested I look into ZignaGenix, a company specializing in stem cells and Natural Killer (NK) cells. After researching their work, I felt this could be the right path for me. NK Cells are designed to strengthen the immune system by boosting white blood cell counts and targeting diseased cells—without harming healthy ones. This non-destructive approach aligned perfectly with my
goal to avoid chemotherapy.
Ryland Dunne, my contact at ZignaGenix was patient, knowledgeable, and diligent in finding answers to all of our questions.
After deciding to move forward, we flew to San Diego and stayed in an Airbnb for the week. (Pro tip: ask Ryland for help with accommodations—he makes it much easier.)
I purchased the NK Cells package, excluding stem cells—300 million cells over five days, Monday through Friday.
Initially, I was uneasy about traveling to Tijuana or staying overnight there, but by Friday, we decided to stay there because it was simply more convenient.
We stayed at Hotel Real del Río, which was fantastic! The breakfast buffet was far from
typical—street tacos, beef roast, pork roast, roasted chicken, birria, ceviche, fresh juices,
eggs, omelets, and much more.
Mauricio, our shuttle driver, made a remarkable impression from day one. He wasn’t just a driver—he was an ambassador for ZignaGenix. Each morning, he greeted us with a genuine smile, enthusiasm, and positivity that set the tone for the day. His knowledge of the area, from San Diego to Tijuana, and his insights into local culture,
geography, food, and bilingualism were incredible. Mauricio went above and beyond his role, making us feel safe, informed, and welcomed at every step. His kindness and professionalism transformed what could have been a stressful experience into one
filled with comfort, trust, and laughter. ZignaGenix is fortunate to have him representing their values and patient care.
As for the clinic—it exceeded all expectations. I had the best week ever, and I credit that to
the incredible ZignaGenix Tijuana team:
• Andrea, the phlebotomist, was so skilled that patients were praising her for leaving no
bruises or marks whatsoever.
• Mariana managed our breakfasts, lunches, and snacks like a pro. Her omelets, energy bars,
beet juice, and coffee were a daily highlight.
• The chef who prepared and delivered our hot meals every morning deserves recognition
too—the food was excellent.
• Anna Karen, the clinical director, went above and beyond to schedule MRI imaging for me at
another hospital, even though I waited until the end of the week to request it.
• Ruben, another shuttle driver, transported me to that hospital and was as professional, kind,
and supportive as anyone could ask for.
• Dr. Oscar Ochoa called me personally before the procedure to answer my questions and
invite further discussion. During treatment, his bedside manner was beyond
compare—genuine, compassionate, and calming. In a moment of gratitude, I told him I loved
him. Without hesitation, he smiled and said he loved me too. It was a simple but unforgettable
gesture of humanity.
• CEO Carlos Ituarte was an unexpected delight—dynamic, humorous, engaging, and
genuinely connected with every patient he met.
Every single person at ZignaGenix went above and beyond to accommodate the patients’
needs. Their philosophy seems to be summed up in one word: “Yes.”
I began the week anxious about being in Tijuana and ended it impressed, grateful, and eager
to return – both to ZignaGenix and the Hotel Real del Río. (I’m still thinking about that
breakfast buffet!). Next time, I’ll make sure to take advantage of their massages, too.
As for the treatments themselves, everything went smoothly. I experienced mild evening
inflammation, but it was unclear whether that was due to diet, activity, or the therapy itself.
Otherwise, I had no complications.
I plan to have my blood work rechecked in about a month, which will determine my next steps. I'll update this review.
Response from ZignagenixOct 16, 2025
Thank you so much for taking the time to share your incredible experience with ZignaGenix Tijuana. Your story and thoughtful detail truly mean the world to our entire team. It’s inspiring to see your strength, openness, and determination to pursue innovative, immune-based therapies—and we’re deeply honored to have been part of your journey.
We’re thrilled to hear that Ryland, Dr. Ochoa, Anna Karen, Andrea, Mariana, Mauricio, Ruben, and the rest of the staff made you feel supported, informed, and cared for at every step. We take great pride in the human side of healing—the smiles, kindness, and genuine connection that make all the difference.
Your words perfectly capture what we strive for every day: compassionate, world-class regenerative care delivered with professionalism and heart. On behalf of everyone at ZignaGenix, thank you for your trust, courage, and positivity. We look forward to welcoming you back soon and continuing this journey toward restored health and vitality.
With gratitude and respect,
Carlos Ituarte
CEO, ZignaGenix
JF
John F.
The service was absolutely fantastic…
The service was absolutely fantastic from start to finish! Everyone was so professional, friendly and attentive. Everything went smoothly and exceeded expectations. Thank you Manie for outstanding service, I would highly recommend!
Response from ZignagenixSep 30, 2025
Thank you so much for sharing your wonderful feedback! We’re thrilled to hear that your experience with us was fantastic from start to finish. Our team takes great pride in being professional, friendly, and attentive, and it’s rewarding to know this stood out to you. We’ll be sure to share your kind words with Manie, who will be delighted to know his outstanding service made such a difference. We truly appreciate your recommendation and look forward to welcoming you again!
JN
Jeff N.
You can't go wrong you're getting your…
You can't go wrong you're getting your treatment here. Everything is top drawer. The shuttle service from San Diego made things super easy and we got there we were greeted by friendly staff with all kinds of food and you could make your custom food order for breakfast or lunch. The doctors were very attentive and highly professional.
Response from ZignagenixSep 26, 2025
Thank you so much for your kind words! We’re delighted to hear that our shuttle service, personalized meals, and attentive care from our doctors made your experience smooth and comfortable. Our goal is to make every step of the journey easy and stress-free, and it means a lot to know we delivered that for you. We truly appreciate your trust and recommendation! 🙏💙
CU
customer
Great customer service
Great customer service. My suggestion is to upgrade the hotels in which clients are staying.
Response from ZignagenixSep 26, 2025
Thank you so much for your kind words about our customer service—we truly appreciate your feedback! We’re always looking for ways to improve the full experience for our clients, and your suggestion regarding hotel accommodations is very helpful. We’ll be reviewing our lodging options to ensure comfort and quality match the level of care we strive to provide. We look forward to welcoming you again soon!
PC
PATRICIA C.
Five Star experience
From airport arrival to departure, care was taken to help navigate us from place to place including friendly contacts by text and phone. The Clinic is so beautiful with staff who greet you at the door. The Doctor answered all questions and explained the process all along. He and the staff worked well together. It's too early to report results, but I'm optimistic they will be beneficial. I was in a pedestrian vs car accident 8 months ago still recovering from left arm and hip fractures.
Be advised: plan to take time to recover gently. They will tell you more.
Response from ZignagenixAug 21, 2025
Thank you so much for your thoughtful 5-star review! 🌟 We’re so glad to hear that you felt supported from the moment you arrived, and that our team and clinic environment helped make your experience smooth and comfortable.
We truly value the trust you’ve placed in us and are happy the doctor and staff were able to answer your questions and guide you through each step of the process. Recovery is a journey, and we appreciate your advice for others to take it gently.
We wish you continued healing and look forward to hearing how your progress unfolds in the coming months. Please don’t hesitate to reach out if you need anything along the way—we’re here for you.
Warm regards,
The ZignaGenix Team
CU
customer
friendly and caring personel
friendly and caring personel
Response from ZignagenixAug 21, 2025
Thank you for your 5-star review! 🌟 We’re delighted to hear that you found our team to be friendly and caring. Providing compassionate care is at the heart of everything we do, and feedback like yours lets us know we’re on the right track. We look forward to supporting you again whenever you need us!
—The ZignaGenix Team