Plexaderm® Skincare began simply with a desire to create products that truly work. From concept to commercial, everything we develop starts with one goal….to deliver REAL RESULTS supported by the latest in scientific and clinical research. Our products are designed to improve the most difficult signs of aging, from instantly reducing the look of wrinkles around the eyes to smoothing the appearance of crepey skin on the delicate neck and chest area. Every Plexaderm Skincare product uses science-backed and time-tested ingredients that provide results you can count on.Product safety is as important to us as product efficacy. Every Plexaderm product goes through a series of industry standard tests and processes to ensure safety, stability, and quality.
Plexaderm® (plexaderm.com) has 711 customer reviews on Five Star Index, with an average rating of 2.9 out of 5.
Also known as
plexaderm.com
Website
plexaderm.com
Category
Salons & Clinics
Location
Boca Raton, Florida
Listed on Five Star Index
2026
About these reviews
Replies
The company replied to 89% of reviews.
Latest
Most recent review: October 2026.
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Reviews are shown as their authors wrote them. The company can reply, but cannot edit them.
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I appreciate Plexaderm's response to my review. I use a water based foundation and not a heavy amount. I also avoided applying any moisturizer or any other product on my clean, dry skin (according to the directions). It's good to acknowledge that this product just does not work on ALL skin types. In reality, NO skin product is cookie-cutter so to admit that it doesn't work for everyone, no matter how much you'd like it to, is a noble gesture indeed.
UB
UBAD
The product gets CRUSTY !
The product DOES work. But.... it eventually becomes CRUSTY appearance on your face and in my specific case, it would become crusty under my eyes. It looks ridiculous. Yes, I tried applying the cream lightly to avoid the crusty look. It you apply it too light, the cream doesn't do it's job. I never apply too much. I apply a small pea size amount under the eye area. No matter what, it gets crusty after about 90 minutes. I also tried applying a hugh quality moisturizing cream on top of the plexaderm cream to avoid the Crusty appearance. But when you do this, the moisturizer defeats the plexaderm product and you clearly see the under eye bag situation. In my humble opinion, there plexaderm formula must be revised and improved so it doesn't become CRUSTY !
Response from Plexaderm®Feb 11, 2026
Thank you for taking the time to share such detailed feedback. We truly appreciate it.
We’re glad to hear that you did see results with the Plexaderm, but we’re very sorry to learn about the crusty appearance you experienced. That’s definitely not the look anyone wants, and we understand how frustrating it must be, especially after carefully experimenting with application amounts and even trying moisturizer on top.
Plexaderm works by forming a temporary tightening layer on the skin, and sometimes excess product, layering with certain skincare formulas (especially oil-based moisturizers), or natural skin hydration levels can affect how it sets. That said, your experience matters, and feedback like yours is incredibly valuable as we continually evaluate and improve our formulas.
If you’re open to it, our customer experience team would love to connect with you directly to review your application routine and offer personalized tips that may help minimize that effect. We also take product improvement suggestions seriously and will be sure your comments are shared with our development team.
Thank you again for your honest review. We truly appreciate you giving Plexaderm a try and sharing your experience.
CU
customer
This product isn't what they claim it to be!
This product isn't living up to its claims. Yes, it does tighten your skin, however, I experienced a burning sensation and when it dried it left a white dried looking appearance on my face. I also applied some moisturizer to see how that would work after drying. That didn't yield the desired results as the undereye bags returned. That was an investment that didn't pay off.
Response from Plexaderm®Jun 9, 2025
Thank you for sharing your experience with us. We’re truly sorry to hear that the Plexaderm Rapid Reduction Serum didn’t meet your expectations and caused discomfort. While it’s great to hear it provided some tightening effect, we understand that the burning sensation and white residue are concerning, and the results didn’t last as hoped after moisturizing. When experiencing sensitivity , we recommend discontinuing use and disposing of any additional product you might have on hand.
Your feedback is very important to us, and we take concerns like yours seriously. We’d love the opportunity to learn more about your experience and make it right. Please reach out to our customer experience team at 1-800-681-0366.
MS
Mont S.
It seems as if this product does not work on African-Americans.
I believe this product does not work on dark skin African-Americans. I have purchased this item 2 times in the last couple of months andI have not received any change whatsoever. Could you help?
Response from Plexaderm®Jun 5, 2025
Thank you for your feedback, and we’re truly sorry to hear that you haven’t seen the results you were expecting. We want to assure you that the Plexaderm is formulated to be effective on all skin tones, including dark skin. Many of our customers from diverse backgrounds have seen positive results. However, we understand that individual results can vary based on several factors, such as skin type, usage consistency, and specific skin concerns. We’d love to learn more about your experience so we can help identify what might be affecting your results.
Please reach out to our customer experience team at 1-800-681-0366 so we can better assist you, and if needed, recommend adjustments or alternative solutions to help you get the best results possible. We value all of our customers and are committed to ensuring that everyone has a positive experience with our products.
DS
Diana S.
I don’t feel that it works as promised
I don’t feel that it works as promised. The lines are still prominent and it actually turns the skin under my eyes a darker color. Pretty disappointed.
Response from Plexaderm®Apr 23, 2025
Thanks for taking the time to leave a review. We are very sorry to hear that the Plexaderm Rapid Reduction Serum did not live up to your expectations. We offer a 30 day money back guarantee on all orders. If your order was made within this time, please give us a call at 1-800-681-0366, we're happy to help. We appreciate you giving Plexaderm a try!
PC
Patricia C.
At first it was a miracle
At first it was a miracle. I was so excited!!!!! It really did work. But..... Then I smiled. And it was a deep disappointment. If you can go all day without making any facial expressions. This product is for you. If not. Don't waste your money.
Response from Plexaderm®Apr 2, 2025
Thanks for taking the time to leave a review. We're happy to hear that the Plexaderm works well for you, however, we're sorry to learn after smiling you were disappointed. Here are some product tips when it comes to applying Plexaderm.
First, apply Plexaderm to a freshly cleansed face. Once applied, it is important to remain still during the Plexaderm application process. Refrain from facial movements for approximately 10 minutes while Plexaderm forms an invisible bond with your skin.
If you're using Plexaderm with makeup, it's best to apply makeup after Plexaderm has set, being as light as possible over the Plexaderm areas and avoiding rubbing. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and applying it with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. Eyeshadows, liner, mascara, and blush are all good products to use with Plexaderm.
Lastly, we recommend using an oil-free moisturizer, as oils break down the tightening effect that Plexaderm creates. Please note that results can vary from product to product. If you're interested, we developed a moisturizer that pairs perfectly with our serum, the Plex-Perfect Daily Moisturizer. You can find it on our website.
Should you need any additional application questions please give us a call at 1-800-681-0366. We're here to help!
SH
Sheri
I tried plexaderm and it was a waste of…
I tried plexaderm and it was a waste of money. I did not see any difference after using it
Response from Plexaderm®Apr 2, 2025
Thanks for your review. We appreciate your honesty and are very sorry that the Plexaderm Rapid Reduction Serum did not meet your expectations. Every purchase comes with a 30-day money-back guarantee. Should your order fall within this time, please give us a call at 1-800-681-0366. We're here to help you!
SS
Shawn S.
Been using your cream for bags and…
Been using your cream for bags and wrinkles for about 3 years now,my last order,it seems like I got an old batch,it’s not going to on as smooth and flaky,which has never happened before,not sure what to do about it just yet,don’t think I’ll be getting it anymore,might try something else
Response from Plexaderm®Mar 3, 2025
Thanks for your review. We're happy to hear you've been using Plexaderm for about 3 years now. However, we are terribly sorry to hear about your recent order. Please give us a call at 1-800-681-0366, we are happy to help!