Plexaderm® Skincare began simply with a desire to create products that truly work. From concept to commercial, everything we develop starts with one goal….to deliver REAL RESULTS supported by the latest in scientific and clinical research. Our products are designed to improve the most difficult signs of aging, from instantly reducing the look of wrinkles around the eyes to smoothing the appearance of crepey skin on the delicate neck and chest area. Every Plexaderm Skincare product uses science-backed and time-tested ingredients that provide results you can count on.Product safety is as important to us as product efficacy. Every Plexaderm product goes through a series of industry standard tests and processes to ensure safety, stability, and quality.
Plexaderm® (plexaderm.com) has 711 customer reviews on Five Star Index, with an average rating of 2.9 out of 5.
Also known as
plexaderm.com
Website
plexaderm.com
Category
Salons & Clinics
Location
Boca Raton, Florida
Listed on Five Star Index
2026
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The company replied to 89% of reviews.
Latest
Most recent review: October 2026.
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This product is not for dark skin people, I've tried it twice and it was awful both times.
Response from Plexaderm®May 12, 2025
Thank you for your feedback, and we're truly sorry to hear about your experience with the Plexaderm Rapid Reduction Serum. We want all of our customers to feel confident and supported when using our products and we understand how frustrating it is when expectations aren't met. While Plexaderm is formulated to work across all skin tones and types, including dark skin, we recognize that results can vary based on individual skin needs and usage. We'd love the chance to better understand what happened and see how we can make this right. Please reach out to our customer experience team directly at 1-800-681-0366 so we can help further.
NO
Noneya
Get rid of this commercial
Get rid of this commercial. I won't ever use this product and can't stand the commercial!
Response from Plexaderm®May 12, 2025
Thanks for sharing your feedback. We're sorry to hear that the commercial didn't resonate with you and that it affected your perception of Plexaderm Rapid Reduction Serum. We aim to create marketing that reflects our values and connects with our audience, but we understand that it doesn't always land as intended. Your input is valuable and we've shared it with our team as part of our ongoing effort to improve. We appreciate you taking the time to let us know how you feel.
MT
Michael T.
Company won't allow purchases with a…
Company won't allow purchases with a gift card!
Response from Plexaderm®May 12, 2025
Thanks for your review. We are very sorry to hear about your purchasing experience with us. Usually, gift cards can be used however, it's important to call the gift card company and update your billing and shipping address to the card you're looking to purchase with. Our systems can be sensitive and may not allow a purchase without this information on file. Should you have any questions, please give us a call at 1-800-681-0366. We're happy to help!
ER
Elliot R.
For me
For me, this product did absolutely nothing. On my forhead wrinkles, before and after...nothing. On wrinkles around my mouth, before and after....nothing. On eye bags, before and after....nothing. In fact, the tightning of skin under my eyes created more wrinkles, that I did not have before using this product. Now understand, these were my results. I can't say how they would work on others. But for me, this product did absolutely nothing.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. We are very sorry to hear about your disappointment
with the Plexadxerm Rapid Reduction Serum. Your satisfaction is important to us and wanted to provide you with some product usage tips when it comes to applying Plexaderm.
You'll want to apply Plexaderm to a freshly cleansed face. Once applied, it is important to remain still during the Plexaderm application process. Refrain from facial movements for approximately 10 minutes while Plexaderm forms an invisible bond with your skin. When applying Plexaderm you need to spread the serum out evenly to avoid over-tighting, which as you mentioned can create more wrinkles.
When using a moisturizer we recommend one that is oil-free, as oils break down the tightening effect that Plexaderm creates. Please note that results can vary from product to product. If you're interested, we developed a moisturizer that pairs perfectly with our serum, the Plex-Perfect Daily Moisturizer.
If you're using Plexaderm with makeup, it's best to apply makeup after Plexaderm has set, being as light as possible over the Plexaderm areas and avoiding rubbing. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. Eyeshadows, liner, mascara, and blush are all good products to use with Plexaderm.
We hope this information was helpful. Should you have any questions or need further assistance, give us a call at 1-800-681-0366. Every purchase is backed with a 30 day money back guarantee, we will be happy to look into your eligibility for you should you decide Plexaderm is not for you.
CT
Christina T.
Plexaderm works if you don't wear…
Plexaderm works if you don't wear makeup. It literally doesn't go under or over makeup and stays on. As soon as you try to use concealor before or after it balls up and come off. Not worth the money. It drys out under you eyes also. My bf used it to and doesn't wear makeup and it only lasted maybe a hour . Not worth the money.
Response from Plexaderm®Apr 28, 2025
Thanks for taking the time to leave a review. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. All makeup brands are different so you may need to adjust the Plexaderm-to-foundation ratio until you get the desired results. We hope this helps, should you need further assistance, please call us at 1-800-681-0366. We're here to help!
CW
Cindi W.
My best friend of 50 years ordered this…
My best friend of 50 years ordered this and put it on before bed. She woke up in the middle of the night and her face was on fire. It was very swollen and had tiny blisters all over her face. She immediately washed it off but the damage was already done! Her eyes were practically swollen shut! The second day her face was worse and her eyes were swollen completely shut. She went to the ER and she is now on two prescriptions to fight the horrible reaction and hopefully heal this mess up and ease the pain she's in!
*If it allowed me to post pics of her on here (I have her permission to do so) I would, and after seeing them I would hope anyone that has their products would throw them away!!
Response from Plexaderm®Apr 22, 2025
Thanks for taking the time to leave a review. We are very sorry to hear about your friends sensitivity to the Plexaxderm Reduction Serum. Plexaderm should only be used during the day and washed off at night before bed time. We recommend discontinuing use and disposing of any remaining product. If you haven't already please give us a call to discuss this matter further at 1-800-681-0366. We're happy to help!
AS
Angela S.
This is a scam and does not make any…
This is a scam and does not make any difference at all! If it did, it would put millions of people out of business. I tried it. Does not work. Just makes your face feel sticky.
Response from Plexaderm®Apr 21, 2025
Thank you for taking the time to leave a review. We're sorry to hear about your disappointment with Plexaderm. Every purchase is backed with a 30 day money back guarantee. If your order was completed within this time, please call us at 1-800-681-0366. We're happy to help!
CE
Cindy E.
No, this one is NOT for real!
Thank goodness I just tried the trial for $14. I bet this company is getting rich off of people getting suckered into trying it. "This one's for real…" is a lie! Do you think anyone would buy it if they knew you cannot use it with any other skin care products? Certainly can't use it with make up! And with me, it didn't work at all. My under eye bags not only did not disappear, they got more pronounced. Smaller, because it tightens skin, but more pronounced because the bags were squeezed into a slightly smaller area which made them stick out more. And of course any effect is very temporary. Because people need to move their face! And most need to put on makeup or sunscreen and moisturizers. I think anybody who says this actually "works" is either lying on purpose or is engaging in extreme wishful thinking.
Response from Plexaderm®Apr 21, 2025
Thank you for taking the time to leave a review. We're sorry to hear about your disappointment with Plexaderm. When using additional cosmetics with Plexaderm Rapid Reduction Serum, water-based products work best. Try mixing 1/3 liquid foundation or concealer with 2/3 Plexaderm and apply with your fingertip. Allow the Plexaderm/foundation mixture to set for 10 minutes. All makeup brands are different so you may need to adjust the Plexaderm-to-foundation ratio until you get the desired results. The Plexaderm formula is quite powerful and if too much is applied you may experience dryness, over tightening, or even see residue. We recommend trying a smaller sized application and spreading it out evenly. Please allow a full 10 minutes for Plexaderm to dry. We do offer a 30 day money back guarantee should the provided tips be less than satisfactory. Should you need additional assistance, please give us a call at 1-800-681-0366. We're happy to help!
