Oxford HealthspanBridging the gap between Eastern wisdom and Western science in the longevity space. First product: Primeadine, premium spermidine supplement.
Oxford Healthspan (oxfordhealthspan.com) has 26 customer reviews on Five Star Index, with an average rating of 4.7 out of 5.
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Personal Care · Orlando, Florida
Excellent
Personal Care · Grants Pass, Oregon
Excellent
Personal Care · Great Neck, NY
Excellent
Personal Care · Costa Mesa, California
Excellent
26 approved reviews, newest moderated first
Danya B.
I've been taking Primeadine for inflammation since I have acne and I want to preserve my fertility. The first thing I noticed is a big jump on my deep sleep, and I feel good knowing my cells are renwing efficiently. Been taking it for 3 years and my acne decreased. Thank you
carrie C.
If I could give zero stars I would have. I had digestive issues with primeadine original. I ordered 5 bottles. I returned 4 unopened bottles after having these issues. But they only refunded 3 bottles. I have been trying for over a month to get the refund for the 4th bottle They don’t guarantee their products as I was only permitted to return unopened bottles. I have contacted Leslie Kay in customer service several times and sent at least 10 emails without any response in solving this problem. It is rhe worst customer service I have ever experienced. Please DO NOT order from this company unless you know you already have no issues with their products.
Response from Oxford HealthspanFeb 17, 2026
Dear Carrie, We’re truly sorry that you felt unheard during this process and that Primeadine Original did not work well for you. Digestive sensitivities can vary from person to person, and we completely understand how frustrating it is when a product doesn’t agree with you. We’d also like to clarify what happened with the refund timing. Your original return request was submitted for one bottle. When additional bottles were later returned, our customer service team needed confirmation from the warehouse that four unopened bottles had been received before issuing the corresponding refund. That confirmation took longer than expected, which is why there was a delay in resolving the matter. We understand how that wait may have felt on your end, and we’re sorry for the frustration it caused. As outlined in our return policy, we are able to refund unopened bottles within the stated return window. Three bottles were refunded promptly once processed, and the remaining bottle was addressed once warehouse verification was completed. We regret that this experience did not meet your expectations and that Primeadine was not the right fit for you. We sincerely wish you the very best in finding a solution that works comfortably for your needs. Kind regards, The Primeadine Team
Valerie Van Horn M.
I’ve been taking Primedine for over 3 years, and it’s a game-changer. When I ran out recently, my sleep went completely haywire — even going to bed at 9 pm, I’d lie awake until 1 or 2 am. Within days of starting a new bottle, I was back to sleeping a full 8 hours. On top of that, it’s also helped with incontinence, which was an unexpected but amazing bonus. Supplements don’t always live up to the hype, but Primedine absolutely does — it works for me, and I couldn’t be happier.
Response from Oxford HealthspanFeb 17, 2026
Dear Valeria, Wow! Thank you so much for your amazing review! We’re absolutely thrilled to hear that you’re having such a positive experience with Primeadine. Our team works hard to create a high-quality product and provide the best possible customer support, so it truly means a lot to know we’ve met (or exceeded!) your expectations. If you ever have any questions or need assistance, we’re always here to help. Thank you again for being part of the Primeadine community! Warm regards, The Primeadine Team
Roddy M.
I have been using Primeadine for just under a year and have noticed a dramatic increase in my deep sleep after about a month of using the product regularly. I also feel more energised in my daily activities.
Response from Oxford HealthspanFeb 17, 2026
Dear Roddy, Thank you so much for sharing your experience and for being with Primeadine for nearly a year! We’re thrilled to hear you’ve noticed such a dramatic improvement in your deep sleep and that you’re feeling more energised in your daily activities. Consistency is key, so it’s fantastic to know that after regular use you’re seeing meaningful results. Your feedback truly means a lot to our team, and we’re grateful to have you as part of the Primeadine community. If you ever have any questions or need support, we’re always here to help. Wishing you continued great sleep and energy! Warm regards, The Primeadine Team
Tracey
Your product prohibits me spending £75 per month and I wonder what is the longer term benefit of taking it for several months if I can't afford taking it longer term? I would need this answered before I would consider taking it at all. many thanks Dr Reid
Response from Oxford HealthspanDec 9, 2024
Hi Dr Reid, thank you for your message. As for our pricing, we prioritize the highest quality, avoiding common additives like industrial seed oils, magnesium stearate, and talc often used in supplements. Unlike cheap synthetic spermidine often "cut" into products, we use food-derived spermidine sourced and manufactured in Japan under strict regulatory standards. Our products undergo rigorous third-party testing to ensure purity and effectiveness. This commitment to quality, like choosing the best ingredients for a child’s birthday cake, is our guiding philosophy. In terms of benefits, you can find out more here: https://oxfordhealthspan.com/blogs/aging-well/the-benefits-of-spermidine-a-full-breakdown. Finally, as you are a doctor, you are welcome to apply to our affiliate program, which would give you a discount off every order for personal use: https://oxfordhealthspan.com/pages/register-affiliate-account
Frank B.
I have used Primeadine for a while now. As a guy I noticed some thinning out of my top corners. Since I use Spermidine I noticed a significant change in the positive direction. I get frequently asked if I color my hair, which I don`t. I realized as well that my sleep is better while using Primeadine. I really like that there is a gluten free choice as well. I just highly recommend Primeadine.
Carmen P.
I have been taking Primedine for over the past 2 months and I have noticed clear improvements on my sleep, levels of energy and my hair. I exercise twice, daily and I never felt so motivated and energetic as I am. Thank you Leslie Kenny for introducing me to this fantastic supplement.
Amrish
Have been taking Primadene now for over a year. Was initially skeptical but have been pleasantly surprised by the impact on my sleep and focus.