Alysha I.
Updated Review - Vial gelling resolved
Kimera chems was able to resolve the issue I had with ARA-290 peptide gelling. The reconstitution instructions are updated on their website and it does require ordering saline or water at pH 7.4 to prevent peptide aggregation as their ARA-290 is not buffered like other vendors I have used. The initial email I received from them was very odd and lacked professionalism (lack of punctuation, odd phrasing, etc), but every email following that has been very professional. I look forward to trying other products from this vendor and updating my review again after receiving my next batch of research supplies.
Response from KimerachemsApr 7, 2026
Thank you for your feedback — we take every review seriously. We want to address this transparently. ARA-290 is well documented across the research community for gelling when reconstituted with standard bacteriostatic water, which typically sits around pH 5.5. This isn't unique to our product — it's a known characteristic of this peptide. It requires a reconstitution vehicle at or above physiological pH (7.4) to remain in solution. A sterile sodium bicarbonate buffer or pH-adjusted vehicle resolves this. If other vendors' ARA-290 dissolves without issue in the same acidic BAC water, that likely means they've incorporated buffering excipients into their lyophilized formulation — which is a valid approach, but it doesn't mean an unbuffered product is defective. It means the reconstitution protocol differs. That said, we should have had this guidance clearly stated on our product page and communicated it better when you reached out. That's a miss on our end and we're correcting it. We'd genuinely like to make this right. Please contact our support team directly and we'll work out a resolution. We appreciate you giving us the opportunity to address this. — Kimera Chems